• Oral Dosage Forms That Should Not Be Crushed | Institute ...

     · Sprycel. Active Ingredient (s) (dasatinib) Dosage Form (s) Tablet. Reasons/Comments. Film-coated (Note: active ingredients are surrounded by wax matrix to prevent healthcare exposure; women who are, or may become, pregnant should not handle crushed or …

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  • What Codependency Is, and What It Isn''t | Psychology Today

     · COMMENTS. I''m known as an expert on codependency, with two published books on the subject. In recent years, however, I have become disturbed by …

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  • Soufeng sanjie formula alleviates collagen-induced ...

     · Rheumatoid arthritis (RA) is a chronic autoimmune disease in which multiple immune cell types and signaling networks malfunction to elicit a maladaptive tissue repair process that leads to organ damage, predominantly in the joints [].The most prominent feature of RA is swelling and deformation of the hands, wrists, feet, and knees [].RA may occur at any age, and the cumulative lifetime risk of ...

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  • JCI

     · The basic pathogenetic feature of postinfectious LA is the development of an excessive, dysregulated proinflammatory immune response during the infection, characterized by exceptionally high IFN-γ levels, which persists in the postinfectious period ().Patients with a polymorphism in the TLR-1 gene who are infected with B.burgdorferi outer surface protein C (OspC) type A (RST1) strains are at ...

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  • A locus coeruleus to dentate gyrus noradrenergic circuit ...

    NE-DGcircuitsaltersaversive contextual learning ... Sean C. Piantadosi, ..., Tammy K. Nguyen, Li Xia, Michael R. Bruchas Correspondence [email protected] In brief Seo et al. implicate a locus coeruleus to dentate gyrus noradrenergic circuit in ... generalization can cause maladaptive fear responses to innoc-uous cues and can severely affect daily ...

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  • Understanding resilience: New approaches for preventing ...

     · Severity and duration of early life stress also matter greatly, as well as timing of positive interventions. For example, studies of children raised in orphanages and later adopted into stable families consistently found that earlier adoption is linked to better outcomes (Rutter, 1998, Rutter, 2013, Tottenham et al., 2010) velopmental timing of adversity itself is also a key factor, with ...

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  • Normal response to threatening situations excessive ...

    Normal response to threatening situations excessive anxiety maladaptive Nearly from AS 200.141 at Johns Hopkins University

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  • Kidney Stone Surgery & Removal Procedures

    Open Surgery. Open surgery is rarely done for kidney stones anymore. But if your stone is very large or it can''t be removed or crushed with other treatments, surgery might be an option.

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  • Edda Spiekerkoetter''s Profile | Stanford Profiles

    Edda Spiekerkoetter is part of Stanford Profiles, official site for faculty, postdocs, students and staff information (Expertise, Bio, Research, Publications, and more). The site facilitates research and collaboration in academic endeavors.

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  • Anxiety and depression in patients with end-stage renal ...

     · Boulware LE, Liu Y, Fink NE, et al. Temporal relation among depression symptoms, cardiovascular disease events, and mortality in end-stage renal disease: contribution of reverse causality. Clin J Am Soc Nephrol. 2006;1(3):496–504. 45. Tsai YC, Chiu YW, Hung CC, et al. Association of symptoms of depression with progression of CKD.

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  • Decreased motivation during chronic pain requires long ...

    Several symptoms associated with chronic pain, including fatigue and depression, are characterized by reduced motivation to initiate or complete goal-directed tasks. However, it is unknown whether maladaptive modifications in ne ural circuits that regulate motivation occur

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  • Bursitis: Types, Causes, Symptoms, Treatment, and Prevention

     · Bursitis is the inflammation or irritation of the bursa. Learn more about the different types, causes, symptoms, prevention, diagnosis, and treatment of bursitis.

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  • Factors Associated With Psychological Distress in Health ...

    Work experience, stigma, maladaptive coping styles, maladaptive personality traits, direct contact with infected cases, time spent in quarantine: McAlonan et al. Hong Kong: Cross-sectional across 2 time points: T1 = 176 T2 = 184 HCW (73.25, T1; 64.50, T2) SARS: T1: 15/04/2003–15/05/2003. During the peak period of hospital admissions for SARS ...

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  • Neuroinflammation and Central Sensitization in Chronic and ...

    Chronic pain is a major health concern that affects one in three Americans and costs the U.S. economy $635 billion dollars each year. 1,2 Acute pain is often elicited by acute inflammation and has biologic significance to protect the wounded tissue. Chronic pain is maladaptive, has no beneficial biologic significance, and is characterized by spontaneous pain (e.g., burning) as well as evoked ...

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  • Psychedelics and reconsolidation of traumatic and ...

     · Clinical data with 3,4-methylenedioxymethamphetamine (MDMA) in post-traumatic stress disorder (PTSD) patients recently stimulated interest on the potential therapeutic use of psychedelics in disorders characterized by maladaptive memories, including substance use disorders (SUD). The rationale for the use of MDMA in PTSD and SUD is being extended to a broader beneficial …

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  • ADHD: Everything You Need to Know

     · Symptoms such as trouble managing time, forgetfulness, and impatience can cause problems at work, home, and in all types of relationships. Find out more about the signs and symptoms …

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  • How to objectively assess and observe maladaptive pain ...

     · Cognitive-affective factors influence the perception of pain and disability. These factors can lead to pain behaviors (PB) that can persist and become maladaptive. These maladaptive PB will further increase the risk of chronicity or persistence of symptoms and disability. Thus, clinicians must be prepared to recognize maladaptive PB in a clinical context.

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  • Post-Treatment Lyme Syndrome and Central Sensitization ...

     · The cause of persistent symptoms after treatment for Lyme disease remains a source of controversy. These symptoms can be quite distressing and debilitating, leading to a functional impairment comparable to that seen in patients with congestive heart failure. These symptoms most commonly include pain, fatigue, depression, and cognitive deficits.

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  • COVID-19: Neurologic complications and management of ...

     · Anosmia and dysgeusia have been reported as common early symptoms in patients with COVID-19, occurring in greater than 80 percent of patients in one series [ 44 ]. In a meta-analysis of 83 studies involving more than 27,000 patients, olfactory dysfunction was reported in 48 percent (95% CI 41.2-54.5) [ 45 ].

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  • Post-Treatment Lyme Syndrome and Central Sensitization ...

     · Lyme Disease: The Extent of the Problem. Lyme disease, the most common vector-borne illness in the United States, is caused by the spirochete Borrelia burgdorferi (hereafter referred to as Bb).According to the Center for Disease Control (CDC)''s nationwide surveillance reports for the year 2010 in the U.S., there were 30,158 new cases of confirmed and probable Lyme disease. 5 These …

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  • Phantom limb

    A phantom limb is the sensation that an amputated or missing limb is still attached. Approximately 80 to of individuals with an amputation experience sensations in their amputated limb. However, only a small percentage will experience painful phantom limb sensation. These sensations are relatively common in amputees and usually resolve within two to three years without treatment.

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  • Cognitive behavioral therapy

    Cognitive behavioral therapy (CBT) is a psycho-social intervention that aims to improve mental health. CBT focuses on challenging and changing cognitive distortions (e.g. thoughts, beliefs, and attitudes) and behaviors, improving emotional regulation, and the development of personal coping strategies that target solving current problems. It was originally designed to treat depression, but its ...

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  • Thrush: Causes, Symptoms, Diagnosis, Treatments & Prevention

    Thrush is a fungal (yeast) infection that can grow in your mouth, throat and other parts of your body. In your mouth thrush appears as a growth that can look like cottage cheese – white, raised lesions on your tongue and cheeks. The condition can quickly become irritated and cause mouth pain and redness. Thrush is caused by the overgrowth of ...

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  • "Am I Going Crazy?!" – SMART Recovery

     · The worst of it lasted almost 4 months, occasionally felt good and normal for max 3-4 days and then severe mental problems kicked in again. After 6 months I had less severe symptoms but still bad enough disturb my everyday life. Most prominent symptoms were anxiety, depression and insomnia. After 1 year the symptoms were less and less severe.

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  • Maladaptive neurovisceral interactions in patients with ...

     · Maladaptive prefrontal‐subcortical inhibition has been reported to be associated with cognitive processing, which plays a critical role in emotional regulation and is found in a wide range of psychopathologies, including depression, anxiety, and schizophrenia. 63 In particular, the dysfunctional frontal‐subcortical/limbic circuits within ...

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  • Why Too Much Self-Control Can Be a Bad Thing

     · This body of research shows that excessive self-control can actually be a problem for some people. This is the central idea behind Radically Open Dialectical Behavior Therapy (RO …

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  • When a Death in the Family Takes Over Your Life ...

     · Caroline was a tall, elegant woman in her late forties, dressed in black from head to toe.* Moments after we met for the first time, she broke down in tears, revealing between sobs the news that ...

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  • Google

    Search the world''s information, including webpages, images, videos and more. Google has many special features to help you find exactly what you''re looking for.

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  • A longitudinal twin and sibling study of the hopelessness ...

     · Conversely, both maladaptive cognitive styles were uniquely associated with depression symptoms after controlling for anxiety, both concurrently and across time (r p = −23 and −0.09 for attributional style and r p = .27 and 0.17 for hopelessness, respectively). Given the lack of unique association between both maladaptive styles and anxiety ...

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  • Personality Disorders

    Personality trait. enduring patterns of behavior exhibited in a wide range of personal contexts. Personality disorder. pervasive, inflexible, extreme, maladaptive personality trait causing impaired functioning or subjective distress. ego syntonic. patient has limited awareness …

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  • Maladaptive Aggression: With a Focus on Impulsive ...

     · Introduction. Aggressive behavior is one of the most common reasons children and adolescents are referred to psychiatric clinics, and it co-occurs with several psychiatric and neurological disorders (Connor 2002; Bam and Connor 2005; Jensen et al. 2007).Clinical levels of aggression in children are associated with significant individual, familial, and societal economic burdens that ...

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  • Hypothyroidism, Particularly Associated with Weight Loss ...

    2 Najarian and Rowsemitt: Hypothyroidism and weight loss.Thyroid Science, 6(6)CR1-7, 2011 of treatment, sometimes with weight regain even whi l e on t re a t ment.[ 4,5] Al ong wi t h a ny we i ght l os s a p-proach, symptoms of low thyroid are common.

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  • The role of rumination in illness trajectories in youth ...

     · (Reference Mezulis, Priess and Hyde 2011) noted that the association was stronger among adolescent , although a further study by the same group highlighted that high levels of depressive symptoms at age 11 were associated with both early puberty and high levels of NE in boys (Mezulis et al. Reference Mezulis, Salk, Hyde, Priess-Groben and ...

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  • Social withdrawal: An initially adaptive behavior that ...

     · In these disorders social withdrawal is often part of a specific "cluster" of symptoms (e.g. negative symptoms in Schizophrenia or neuropsychiatric symptoms in Alzheimer''s disease). Moreover, social withdrawal is the core behavioral symptom of social anxiety disorder (SAD) that is a highly prevalent disorder characterized by persistent ...

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  • 12.00-Mental Disorders-Adult

    Preoccupation with having or acquiring a serious illness without significant symptoms present. AND. Extreme limitation of one, or marked limitation of two, of the following areas of mental functioning (see 12.00F ): Understand, remember, or apply information (see 12.00E1 ).

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  • Frontiers | Prevalence and Influencing Factors of Anxiety ...

     · BackgroundThe outbreak of novel coronavirus pneumonia (COVID-19) has brought enormous physical and psychological pressure on Chinese medical staff. It is extremely important to understand the prevalence and influencing factors of anxiety and depression symptoms in first-line anti-epidemic medical staff and their coping styles for these negative emotions.MethodsA cross …

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  • Osteoarthritis: toward a comprehensive understanding of ...

     · Osteoarthritis (OA) is the most common degenerative joint disease and a major cause of pain and disability in adult individuals. The etiology of OA …

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  • Systemic Lupus Erythematosus (SLE): Practice Essentials ...

     · Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by antibodies to nuclear and cytoplasmic antigens, multisystem inflammation, protean clinical manifestations, and a relapsing and remitting course. More than 90% of cases of SLE occur in women, frequently starting at childbearing age. See the image below.

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  • Depression in Parents, Parenting, and Children ...

    Lim, Wood, and Miller (2008), in a study of mothers with depressive symptoms and their children (n = 242, ages 7â 17) with asthma symptoms recruited from pediatric emergency departments, also found evidence consistent with nega- tive parenting as a partial mediator of the relation between maternal depres- sive symptoms and childrenâ s ...

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  • The Relative Health Benefits of Different Sexual ...

    Immature (maladaptive) defense mechanisms involve a distortion of reality and/or impairment of awareness, and they are associated with a variety of indices of poorer mental health and relatedness, including psychological immaturity and lesser ability to relate intimately with the opposite 24, 25.

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